Asymmetric total synthesis of erythromcin. 1. Synthesis of an erythronolide A secoacid derivative via asymmetric induction

Click to copy article linkArticle link copied!

This article is cited by 240 publications.

1. Maria L. Adrover-Castellano, Brian J. Curtis, Jennifer J. Schmidt, Hannah A. Boesger, Carolyn A. Glasser, Damilola E. Olukorede, Fengrui Qu, David H. Sherman. Directed Evolution of a Modular Polyketide Synthase Thioesterase for Generation of a Hybrid Macrocyclic Ring System. ACS Catalysis 2025, 15 (4) , 3405-3417. https://doi.org/10.1021/acscatal.4c07922
2. Tobias Morack, Carina Onneken, Hiroshi Nakakohara, Christian Mück-Lichtenfeld, Ryan Gilmour. Enantiodivergent Prenylation via Deconjugative Isomerization. ACS Catalysis 2021, 11 (19) , 11929-11937. https://doi.org/10.1021/acscatal.1c03089
3. Jennifer Alisa Amrhein, Stefan Knapp, Thomas Hanke. Synthetic Opportunities and Challenges for Macrocyclic Kinase Inhibitors. Journal of Medicinal Chemistry 2021, 64 (12) , 7991-8009. https://doi.org/10.1021/acs.jmedchem.1c00217
4. Marta De Zotti, Jonathan Clayden. Extended Diethylglycine Homopeptides Formed by Desulfurization of Their Tetrahydrothiopyran Analogues. Organic Letters 2019, 21 (7) , 2209-2212. https://doi.org/10.1021/acs.orglett.9b00501
5. Francesco Manoni, Corentin Rumo, Liubo Li, and Patrick G. Harran . Unconventional Fragment Usage Enables a Concise Total Synthesis of (−)-Callyspongiolide. Journal of the American Chemical Society 2018, 140 (4) , 1280-1284. https://doi.org/10.1021/jacs.7b13591
6. Stephen F. Martin . Natural Products and Their Mimics as Targets of Opportunity for Discovery. The Journal of Organic Chemistry 2017, 82 (20) , 10757-10794. https://doi.org/10.1021/acs.joc.7b01368
7. Sean E. Rossiter, Madison H. Fletcher, and William M. Wuest . Natural Products as Platforms To Overcome Antibiotic Resistance. Chemical Reviews 2017, 117 (19) , 12415-12474. https://doi.org/10.1021/acs.chemrev.7b00283
8. Eric J. Alexy, Scott C. Virgil, Michael D. Bartberger, and Brian M. Stoltz . Enantioselective Pd-Catalyzed Decarboxylative Allylic Alkylation of Thiopyranones. Access to Acyclic, Stereogenic α-Quaternary Ketones. Organic Letters 2017, 19 (19) , 5007-5009. https://doi.org/10.1021/acs.orglett.7b02354
9. Christopher R. Shugrue and Scott J. Miller . Applications of Nonenzymatic Catalysts to the Alteration of Natural Products. Chemical Reviews 2017, 117 (18) , 11894-11951. https://doi.org/10.1021/acs.chemrev.7b00022
10. Julia Wildt, Anna C. Brezny, and Clark R. Landis . Backbone-Modified Bisdiazaphospholanes for Regioselective Rhodium-Catalyzed Hydroformylation of Alkenes. Organometallics 2017, 36 (16) , 3142-3151. https://doi.org/10.1021/acs.organomet.7b00475
11. Samson Afewerki and Armando Córdova . Combinations of Aminocatalysts and Metal Catalysts: A Powerful Cooperative Approach in Selective Organic Synthesis. Chemical Reviews 2016, 116 (22) , 13512-13570. https://doi.org/10.1021/acs.chemrev.6b00226
12. Libing Yu, Huan Wang, Novruz G. Akhmedov, Christopher Sowa, Kai Liu, Hiyun Kim, and Lawrence Williams . Direct Entry to 4,10-Didesmethyl (9S)-Dihydroerythronolide A via Catalytic Allene Osmylation. Organic Letters 2016, 18 (12) , 2868-2871. https://doi.org/10.1021/acs.orglett.6b01151
13. Madhurjya Borah, Paramartha Gogoi, Kiran Indukuri, and Anil K. Saikia . Diastereoselective Synthesis of Substituted Tetrahydrothiophenes and -thiopyrans via Thia-Prins Cyclization Reaction. The Journal of Organic Chemistry 2015, 80 (5) , 2641-2648. https://doi.org/10.1021/jo502831w
14. Emily J. Tollefson, David D. Dawson, Charlotte A. Osborne, and Elizabeth R. Jarvo . Stereospecific Cross-Coupling Reactions of Aryl-Substituted Tetrahydrofurans, Tetrahydropyrans, and Lactones. Journal of the American Chemical Society 2014, 136 (42) , 14951-14958. https://doi.org/10.1021/ja5076426
15. Douglas A. Hansen, Christopher M. Rath, Eli B. Eisman, Alison R. H. Narayan, Jeffrey D. Kittendorf, Jonathan D. Mortison, Yeo Joon Yoon, and David H. Sherman . Biocatalytic Synthesis of Pikromycin, Methymycin, Neomethymycin, Novamethymycin, and Ketomethymycin. Journal of the American Chemical Society 2013, 135 (30) , 11232-11238. https://doi.org/10.1021/ja404134f
16. B. V. Subba Reddy, A. Venkateswarlu, Prashant Borkar, J. S. Yadav, M. Kanakaraju, A. C. Kunwar, and B. Sridhar . Thia-Prins Bicyclization Approach for the Stereoselective Synthesis of Dithia- and Azathia-Bicycles. The Journal of Organic Chemistry 2013, 78 (12) , 6303-6308. https://doi.org/10.1021/jo400680w
17. Linda Celeste Montemiglio, Alberto Macone, Chiara Ardiccioni, Giovanna Avella, Beatrice Vallone, and Carmelinda Savino . Redirecting P450 EryK Specificity by Rational Site-Directed Mutagenesis. Biochemistry 2013, 52 (21) , 3678-3687. https://doi.org/10.1021/bi400223j
18. Colin J. B. Harvey, Joseph D. Puglisi, Vijay S. Pande, David E. Cane, and Chaitan Khosla . Precursor Directed Biosynthesis of an Orthogonally Functional Erythromycin Analogue: Selectivity in the Ribosome Macrolide Binding Pocket. Journal of the American Chemical Society 2012, 134 (29) , 12259-12265. https://doi.org/10.1021/ja304682q
19. Somasekhar Bondalapati, Paramartha Gogoi, Kiran Indukuri, and Anil K. Saikia . Diastereoselective Synthesis of Substituted Tetrahydrothiopyrans via (3,5)-Thionium–Ene Cyclization Reaction. The Journal of Organic Chemistry 2012, 77 (5) , 2508-2512. https://doi.org/10.1021/jo2023944
20. Hong-Se Oh and Han-Young Kang . Total Synthesis of Pikromycin. The Journal of Organic Chemistry 2012, 77 (2) , 1125-1130. https://doi.org/10.1021/jo201158q
21. B. V. Subba Reddy, Prashant Borkar, J. S. Yadav, B. Sridhar, and René Grée . Tandem Prins/Friedel–Crafts Cyclization for Stereoselective Synthesis of Heterotricyclic Systems. The Journal of Organic Chemistry 2011, 76 (19) , 7677-7690. https://doi.org/10.1021/jo201027u
22. Kai Liu, Hiyun Kim, Partha Ghosh, Novruz G. Akhmedov, and Lawrence J. Williams . Direct Entry to Erythronolides via a Cyclic Bis[Allene]. Journal of the American Chemical Society 2011, 133 (38) , 14968-14971. https://doi.org/10.1021/ja207496p
23. Albert Moyano and Ramon Rios . Asymmetric Organocatalytic Cyclization and Cycloaddition Reactions. Chemical Reviews 2011, 111 (8) , 4703-4832. https://doi.org/10.1021/cr100348t
24. Dieter Muri and Erick M. Carreira. Stereoselective Synthesis of Erythronolide A via Nitrile Oxide Cycloadditions and Related Studies. The Journal of Organic Chemistry 2009, 74 (22) , 8695-8712. https://doi.org/10.1021/jo901817b
25. Abigail G. Doyle and, Eric N. Jacobsen. Small-Molecule H-Bond Donors in Asymmetric Catalysis. Chemical Reviews 2007, 107 (12) , 5713-5743. https://doi.org/10.1021/cr068373r
26. Anniina Erkkilä,, Inkeri Majander, and, Petri M. Pihko. Iminium Catalysis. Chemical Reviews 2007, 107 (12) , 5416-5470. https://doi.org/10.1021/cr068388p
27. Gary E. Keck and, Gregory D. Lundquist. Synthetic Studies toward the Total Synthesis of Swinholide. 1. Stereoselective Construction of the C19−C35 Subunit. The Journal of Organic Chemistry 1999, 64 (12) , 4482-4491. https://doi.org/10.1021/jo990291y
28. Masahiko Yamaguchi,, Tai Shiraishi, and, Masahiro Hirama. Asymmetric Michael Addition of Malonate Anions to Prochiral Acceptors Catalyzed by l-Proline Rubidium Salt. The Journal of Organic Chemistry 1996, 61 (10) , 3520-3530. https://doi.org/10.1021/jo960216c
29. Maryam Mousavi-Ebadia, Javad Safaei-Ghomi, Masoumeh Jadidi Nejad. Synthesis of thiopyran derivatives via [4 + 2] cycloaddition reactions. RSC Advances 2025, 15 (14) , 11160-11188. https://doi.org/10.1039/D5RA01222H
30. . Macrolide Glycosides. 2024, 89-118. https://doi.org/10.1002/9783527817894.ch5
31. Thaddeus Q. Paulsel, Gavin J. Williams. Current State‐of‐the‐Art Toward Chemoenzymatic Synthesis of Polyketide Natural Products. ChemBioChem 2023, 24 (21) https://doi.org/10.1002/cbic.202300386
32. Gerhard Klebe. Biopharmaka: Peptide, Proteine, Nucleotide und Makrolide als Wirkstoffe. 2023, 701-732. https://doi.org/10.1007/978-3-662-67209-9_32
33. A. Córdova, K. Zhang, L. Deiana. 4 Organocatalytic Dynamic Kinetic Asymmetric Transformations. 2023https://doi.org/10.1055/sos-SD-237-00049
34. Bram Ryckaert, Ellen Demeyere, Frederick Degroote, Hilde Janssens, Johan M Winne. 1,4-Dithianes: attractive C2-building blocks for the synthesis of complex molecular architectures. Beilstein Journal of Organic Chemistry 2023, 19 , 115-132. https://doi.org/10.3762/bjoc.19.12
35. Ramesh Ramapanicker, Vinod K. Singh. Nobel Prize in Chemistry 2021. Resonance 2022, 27 (12) , 2161-2181. https://doi.org/10.1007/s12045-022-1512-1
36. Tomoka Dentani, Ayano Kawachi, Misaki Kato, Tomoyuki Yoshimura, Jun-ichi Matsuo. Cascade cyclization of 1,2,7,8-tetraones and total synthesis of (±)-nesteretal A. Organic Chemistry Frontiers 2022, 9 (14) , 3786-3793. https://doi.org/10.1039/D2QO00740A
37. Timothy Patrick McFadden, Chideraa Iheanyi Nwachukwu, Andrew George Roberts. An amine template strategy to construct successive C–C bonds: synthesis of benzo[ h ]quinolines by a deaminative ring contraction cascade. Organic & Biomolecular Chemistry 2022, 20 (7) , 1379-1385. https://doi.org/10.1039/D1OB02245H
38. Gen Li, Mingliang Lou, Xiangbing Qi. A brief overview of classical natural product drug synthesis and bioactivity. Organic Chemistry Frontiers 2022, 9 (2) , 517-571. https://doi.org/10.1039/D1QO01341F
39. . The Woodwardian Synthesis of Erythromycin A. Synfacts 2021, 0705. https://doi.org/10.1055/s-0040-1719754
40. Stephen G. Davies, Ai M. Fletcher, Paul M. Roberts, James E. Thomson. Mutual kinetic resolution: probing enantiorecognition phenomena and screening for kinetic resolution with racemic reagents. Organic & Biomolecular Chemistry 2021, 19 (13) , 2847-2855. https://doi.org/10.1039/D0OB02151B
41. Prathama S. Mainkar, Ambica Vankamamidi, Srivari Chandrasekhar. More Twins in the Scientific Literature of the 21st Century. Angewandte Chemie 2021, 133 (2) , 552-556. https://doi.org/10.1002/ange.201915777
42. Prathama S. Mainkar, Ambica Vankamamidi, Srivari Chandrasekhar. More Twins in the Scientific Literature of the 21st Century. Angewandte Chemie International Edition 2021, 60 (2) , 544-548. https://doi.org/10.1002/anie.201915777
43. Moritz Weiß, Martin Brehm. Exploring Free Energy Profiles of Enantioselective Organocatalytic Aldol Reactions under Full Solvent Influence. Molecules 2020, 25 (24) , 5861. https://doi.org/10.3390/molecules25245861
44. Maria C.K. Sakukuma, Manoel A.M. Filho, Roberto Rivelino, Mauricio M. Victor. Use of organocatalysis for the synthesis of phenyl-hydroxylated-butyric acids. Tetrahedron Letters 2020, 61 (43) , 152431. https://doi.org/10.1016/j.tetlet.2020.152431
45. Robert R. A. Freund, Matthias van den Borg, Daniel Gaissmaier, Robin Schlosser, Timo Jacob, Hans‐Dieter Arndt. Cornforth–Evans Transition States in Stereocontrolled Allylborations of Epoxy Aldehydes. Chemistry – A European Journal 2020, 26 (39) , 8639-8650. https://doi.org/10.1002/chem.202001479
46. Yinhui Qin, Shutao Ma. Recent Advances in the Development of Macrolide Antibiotics as Antimicrobial Agents. Mini-Reviews in Medicinal Chemistry 2020, 20 (7) , 601-625. https://doi.org/10.2174/1389557520666191223160942
47. Arianna Sinibaldi, Valeria Nori, Andrea Baschieri, Francesco Fini, Antonio Arcadi, Armando Carlone. Organocatalysis and Beyond: Activating Reactions with Two Catalytic Species. Catalysts 2019, 9 (11) , 928. https://doi.org/10.3390/catal9110928
48. Pei‐Qiang Huang. Introduction. 2018, 1-25. https://doi.org/10.1002/9781118940228.ch0
49. Kyriacos C Nicolaou, Stephan Rigol. A brief history of antibiotics and select advances in their synthesis. The Journal of Antibiotics 2018, 71 (2) , 153-184. https://doi.org/10.1038/ja.2017.62
50. Sulejman Alihodžić, Mirjana Bukvić, Ivaylo J. Elenkov, Antun Hutinec, Sanja Koštrun, Dijana Pešić, Gordon Saxty, Linda Tomašković, Dinko Žiher. Current Trends in Macrocyclic Drug Discovery and beyond -Ro5. 2018, 113-233. https://doi.org/10.1016/bs.pmch.2018.01.002
51. Felix Scheidt, Philipp Selter, Nico Santschi, Mareike C. Holland, Dmytro V. Dudenko, Constantin Daniliuc, Christian Mück‐Lichtenfeld, Michael Ryan Hansen, Ryan Gilmour. Emulating Natural Product Conformation by Cooperative, Non‐Covalent Fluorine Interactions. Chemistry – A European Journal 2017, 23 (25) , 6142-6149. https://doi.org/10.1002/chem.201604632
52. Prabhavathi Fernandes, Evan Martens, David Pereira. Nature nurtures the design of new semi-synthetic macrolide antibiotics. The Journal of Antibiotics 2017, 70 (5) , 527-533. https://doi.org/10.1038/ja.2016.137
53. Weiwei Zhang, Lina Qiu, Aijun Gong, Xiaotao Yuan. Isolation and characterization of a high-efficiency erythromycin A-degrading Ochrobactrum sp. strain. Marine Pollution Bulletin 2017, 114 (2) , 896-902. https://doi.org/10.1016/j.marpolbul.2016.10.076
54. Jan Wallbaum, Daniel B Werz. Synthesis of 1,3- cis -disubstituted sterically encumbered imidazolidinone organocatalysts. Beilstein Journal of Organic Chemistry 2017, 13 , 2577-2583. https://doi.org/10.3762/bjoc.13.254
55. Aurélie Claraz, Juha H. Siitonen, Petri M. Pihko. Iminium Catalysis ( n ?→?π * ). 2016, 805-856. https://doi.org/10.1002/9783527675142.ch16
56. Sabine Wallbaum, Jürgen Martens, Frederic Minassian, Nicholas G. Jentsch. ( S )-Proline. 2016, 1-23. https://doi.org/10.1002/047084289X.rp258.pub3
57. Alexander Arndt, Tom Kunde, Rainer Mahrwald. Logic of organic chemistry. ChemTexts 2016, 2 (1) https://doi.org/10.1007/s40828-015-0020-2
58. Markus Kalesse, Andreas Böhm, Andi Kipper, Vanessa Wandelt. Synthesis of Antibiotics. 2016, 419-445. https://doi.org/10.1007/82_2016_502
59. Ding-wei Huang. Temporal evolution of multi-author papers in basic sciences from 1960 to 2010. Scientometrics 2015, 105 (3) , 2137-2147. https://doi.org/10.1007/s11192-015-1760-x
60. Felix Bächle, Michael Hanack, Thomas Ziegler. Synthesis and Spectroscopic Evaluation of Two Novel Glycosylated Zinc(II)-Phthalocyanines. Molecules 2015, 20 (10) , 18367-18386. https://doi.org/10.3390/molecules201018367
61. Nikolaus G. Turrini, Mélanie Hall, Kurt Faber. Enzymatic Synthesis of Optically Active Lactones via Asymmetric Bioreduction using Ene‐Reductases from the Old Yellow Enzyme Family. Advanced Synthesis & Catalysis 2015, 357 (8) , 1861-1871. https://doi.org/10.1002/adsc.201500094
62. Mareike C. Holland, Ryan Gilmour. Dekonstruktion kovalenter Organokatalyse. Angewandte Chemie 2015, 127 (13) , 3934-3943. https://doi.org/10.1002/ange.201409004
63. Mareike C. Holland, Ryan Gilmour. Deconstructing Covalent Organocatalysis. Angewandte Chemie International Edition 2015, 54 (13) , 3862-3871. https://doi.org/10.1002/anie.201409004
64. Steffen Friedrich, Frank Hahn. Opportunities for enzyme catalysis in natural product chemistry. Tetrahedron 2015, 71 (10) , 1473-1508. https://doi.org/10.1016/j.tet.2014.12.026
65. . Seven‐, Eight‐Membered and Larger Heterocyclic Rings and Their Fused Derivatives. 2015, 649-755. https://doi.org/10.1002/9781118960554.ch7
66. Gerrit Jürjens, Andreas Kirschning, David A. Candito. Lessons from the Synthetic Chemist Nature. Natural Product Reports 2015, 32 (5) , 723-737. https://doi.org/10.1039/C4NP00160E
67. Zhong‐Yan Cao, Feng Zhu, Jian Zhou. Multicatalyst System. 2014, 37-157. https://doi.org/10.1002/9781118846919.ch2
68. . Protection for the Hydroxyl Group, Including 1,2‐ and 1,3‐Diols. 2014, 17-471. https://doi.org/10.1002/9781118905074.ch02
69. . Protection for the Amino Group. 2014, 895-1193. https://doi.org/10.1002/9781118905074.ch07
70. Peter M. Wright, Ian B. Seiple, Andrew G. Myers. Zur Rolle der chemischen Synthese in der Entwicklung antibakterieller Wirkstoffe. Angewandte Chemie 2014, 126 (34) , 8984-9014. https://doi.org/10.1002/ange.201310843
71. Peter M. Wright, Ian B. Seiple, Andrew G. Myers. The Evolving Role of Chemical Synthesis in Antibacterial Drug Discovery. Angewandte Chemie International Edition 2014, 53 (34) , 8840-8869. https://doi.org/10.1002/anie.201310843
72. Isak Rajjak Shaikh. Organocatalysis: Key Trends in Green Synthetic Chemistry, Challenges, Scope towards Heterogenization, and Importance from Research and Industrial Point of View. Journal of Catalysts 2014, 2014 , 1-35. https://doi.org/10.1155/2014/402860
73. Waleed Salih, Philip M. Short, Stuart Schembri. Macrolides as anti-inflammatory agents in CAP. 2014https://doi.org/10.1183/1025448x.10004713
74. Isamu Shiina. An Adventurous Synthetic Journey with MNBA from Its Reaction Chemistry to the Total Synthesis of Natural Products. Bulletin of the Chemical Society of Japan 2014, 87 (2) , 196-233. https://doi.org/10.1246/bcsj.20130216
75. N. Mase, Y. Hayashi. 2.07 The Aldol Reaction: Organocatalysis Approach. 2014, 273-339. https://doi.org/10.1016/B978-0-08-097742-3.00208-1
76. C.H. Heathcock. 2.08 The Aldol Reaction: Group I and Group II Enolates. 2014, 340-395. https://doi.org/10.1016/B978-0-08-097742-3.00209-3
77. Shouliang Yang, Yumeng Xi, Jia-Hua Chen, Zhen Yang. Asymmetric total synthesis of (−)-cebulactam A1. Organic Chemistry Frontiers 2014, 1 (1) , 91. https://doi.org/10.1039/c3qo00036b
78. Aman Mahajan, Renate Hans, Kelly Chibale, Vipan Kumar. Synthesis and medicinal chemistry of selected antitubercular natural products and natural product derivatives. RSC Advances 2014, 4 (29) , 15180. https://doi.org/10.1039/c3ra46124f
79. Mariette M. Pereira, Ângela C.B. Neves, Mário J.F. Calvete, Lucas D. Dias, Auguste Fernandes. Binol derivative ligand immobilized onto silica: Alkyl-cyanohydrin synthesis via sequential hydroformylation/heterogeneous cyanosilylation reactions. Catalysis Today 2013, 218-219 , 99-106. https://doi.org/10.1016/j.cattod.2013.09.050
80. Ramon Rios, Xavier Companyó. Addition to α,β‐Unsaturated Aldehydes and Ketones. 2013, 975-1012. https://doi.org/10.1002/9783527658862.ch33
81. Hélène Pellissier. Formation of 3‐, 4‐ and 5‐Membered Cycles by Intermolecular Reactions. 2013, 1091-1130. https://doi.org/10.1002/9783527658862.ch37
82. Ramon Rios, Xavier Companyó. Introduction: A Historical Point of View. 2013, 1-10. https://doi.org/10.1002/9781118604755.ch01
83. Feng Xu. Organocatalysis for Asymmetric Synthesis: From Lab To Factory. 2013, 317-337. https://doi.org/10.1002/9781118354520.ch14
84. A. S. Kucherenko, D. E. Siyutkin, R. R. Dashkin, S. G. Zlotin. Organocatalysis of asymmetric aldol reaction in water: comparison of catalytic properties of (S)-valine and (S)-proline amides. Russian Chemical Bulletin 2013, 62 (4) , 1010-1015. https://doi.org/10.1007/s11172-013-0132-z
85. Gabriela Guillena. Organocatalyzed Aldol Reactions. 2013, 155-268. https://doi.org/10.1002/9783527656714.ch3
86. David H. Woodmansee, Marc‐André Müller, Lars Tröndlin, Esther Hörmann, Andreas Pfaltz. Asymmetric Hydrogenation of α,β‐Unsaturated Carboxylic Esters with Chiral Iridium N,P Ligand Complexes. Chemistry – A European Journal 2012, 18 (43) , 13780-13786. https://doi.org/10.1002/chem.201202397
87. Junichiro Yamaguchi, Atsushi D. Yamaguchi, Kenichiro Itami. Funktionalisierung von C‐H‐Bindungen: neue Synthesemethoden für Naturstoffe und Pharmazeutika. Angewandte Chemie 2012, 124 (36) , 9092-9142. https://doi.org/10.1002/ange.201201666
88. William A. Nugent. Black‐Swan‐Ereignisse in der organischen Synthese. Angewandte Chemie 2012, 124 (36) , 9066-9080. https://doi.org/10.1002/ange.201202348
89. Junichiro Yamaguchi, Atsushi D. Yamaguchi, Kenichiro Itami. CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals. Angewandte Chemie International Edition 2012, 51 (36) , 8960-9009. https://doi.org/10.1002/anie.201201666
90. William A. Nugent. “Black Swan Events” in Organic Synthesis. Angewandte Chemie International Edition 2012, 51 (36) , 8936-8949. https://doi.org/10.1002/anie.201202348
91. . Polyketides. 2012, 187-217. https://doi.org/10.1002/9781118347300.ch7
92. Qian Wang, Jie‐Ping Zhu, Kyriacos C. Nicolaou, Henry N. C. Wong, Wei‐Dong Li. Total Synthesis of Natural Products and the Synergy with Synthetic Methodology. 2012, 33-79. https://doi.org/10.1002/9783527664801.ch2
93. . Macrolide Antibiotics. 2012, 173-196. https://doi.org/10.1002/9781118325421.ch8
94. Corinna Reisinger. Background. 2012, 5-40. https://doi.org/10.1007/978-3-642-28118-1_2
95. Robert E. Gawley, Jeffrey Aubé. Practical Aspects of Asymmetric Synthesis. 2012, 63-95. https://doi.org/10.1016/B978-0-08-044860-2.00002-7
96. J. Mulzer. 2.2 General Principles of Diastereoselective Reactions: Rigid Templates. 2012, 9-44. https://doi.org/10.1016/B978-0-08-095167-6.00204-4
97. M. Braun. 2.12 Selected Diastereoselective Reactions: Additions of Achiral Carbanions to Chiral Aldehydes and Ketones. 2012, 346-369. https://doi.org/10.1016/B978-0-08-095167-6.00207-X
98. Laëtitia Chausset-Boissarie, Roman Àrvai, Graham R. Cumming, Laure Guénée, E. Peter Kündig. Asymmetric synthesis of (+)-vertine and (+)-lythrine. Organic & Biomolecular Chemistry 2012, 10 (32) , 6473. https://doi.org/10.1039/c2ob25880c
99. Lucie E. Zimmer, Christof Sparr, Ryan Gilmour. Konformative Fluoreffekte in der Organokatalyse: eine neuartige Strategie zum molekularen Design. Angewandte Chemie 2011, 123 (50) , 12062-12074. https://doi.org/10.1002/ange.201102027
100. Lucie E. Zimmer, Christof Sparr, Ryan Gilmour. Fluorine Conformational Effects in Organocatalysis: An Emerging Strategy for Molecular Design. Angewandte Chemie International Edition 2011, 50 (50) , 11860-11871. https://doi.org/10.1002/anie.201102027