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(33)
, 9341-9346. https://doi.org/10.1021/acs.orglett.5c03049
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, 26387-26396. https://doi.org/10.1021/jacs.4c09276
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, 2224-2239. https://doi.org/10.1021/acs.oprd.2c00139
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(46)
, 13735-13742. https://doi.org/10.1021/acs.langmuir.0c01485
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(14)
, 7719-7733. https://doi.org/10.1021/acscatal.0c02032
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, 4710-4715. https://doi.org/10.1021/acs.orglett.0c01501
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(8)
, 3721-3748. https://doi.org/10.1021/acs.chemrev.0c00053
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(11)
, 2767-2774. https://doi.org/10.1021/acs.langmuir.0c00198
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(9)
, 4379-4389. https://doi.org/10.1021/jacs.9b13156
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(22)
, 14712-14723. https://doi.org/10.1021/acs.joc.9b02296
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(5)
, 8862-8873. https://doi.org/10.1021/acsomega.9b00465
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(9)
, 5236-5244. https://doi.org/10.1021/acs.joc.9b00220
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(6)
, 4221-4260. https://doi.org/10.1021/acs.chemrev.8b00583
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(3)
, 1247-1256. https://doi.org/10.1021/acs.joc.8b02644
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(39)
, 7842-7851. https://doi.org/10.1021/acs.jpca.8b07229
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(9)
, 2572-2575. https://doi.org/10.1021/acs.orglett.8b00771
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(1)
, 350-363. https://doi.org/10.1021/acs.joc.7b02745
- Polyssena Renzi, Johnny Hioe, Ruth M. Gschwind. Enamine/Dienamine and Brønsted Acid Catalysis: Elusive Intermediates, Reaction Mechanisms, and Stereoinduction Modes Based on in Situ NMR Spectroscopy and Computational Studies. Accounts of Chemical Research 2017, 50
(12)
, 2936-2948. https://doi.org/10.1021/acs.accounts.7b00320
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(15)
, 3958-3961. https://doi.org/10.1021/acs.orglett.7b01622
- Zhi-Long Jia, Yao Wang, Chuan-Gang Zhao, Xiao-Hai Zhang, and Peng-Fei Xu . Highly Enantioselective Construction of Hajos–Wiechert Ketone Skeletons via an Organocatalytic Vinylogous Michael/Stetter Relay Sequence. Organic Letters 2017, 19
(8)
, 2130-2133. https://doi.org/10.1021/acs.orglett.7b00767
- Santiago Cañellas, Carles Ayats, Andrea H. Henseler, and Miquel A. Pericàs . A Highly Active Polymer-Supported Catalyst for Asymmetric Robinson Annulations in Continuous Flow. ACS Catalysis 2017, 7
(2)
, 1383-1391. https://doi.org/10.1021/acscatal.6b03286
- Samson Afewerki and Armando Córdova . Combinations of Aminocatalysts and Metal Catalysts: A Powerful Cooperative Approach in Selective Organic Synthesis. Chemical Reviews 2016, 116
(22)
, 13512-13570. https://doi.org/10.1021/acs.chemrev.6b00226
- Wafa Gati and Hisashi Yamamoto . Second Generation of Aldol Reaction. Accounts of Chemical Research 2016, 49
(9)
, 1757-1768. https://doi.org/10.1021/acs.accounts.6b00243
- Ana Bahamonde and Paolo Melchiorre . Mechanism of the Stereoselective α-Alkylation of Aldehydes Driven by the Photochemical Activity of Enamines. Journal of the American Chemical Society 2016, 138
(25)
, 8019-8030. https://doi.org/10.1021/jacs.6b04871
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(6)
, 1279-1291. https://doi.org/10.1021/acs.accounts.6b00204
- Arun Raja, Bor-Cherng Hong, Ju-Hsiou Liao, and Gene-Hsiang Lee . Organocatalytic Enantioselective Michael–Michael–Henry Reaction Cascade. An Entry to Highly Functionalized Hajos–Parrish-Type Ketones with Five to Six Contiguous Stereogenic Centers and Two Quaternary Carbons. Organic Letters 2016, 18
(8)
, 1760-1763. https://doi.org/10.1021/acs.orglett.6b00459
- Chun Liu, E. Zachary Oblak, Mark N. Vander Wal, Andrew K. Dilger, Danielle K. Almstead, and David W. C. MacMillan . Oxy-Allyl Cation Catalysis: An Enantioselective Electrophilic Activation Mode. Journal of the American Chemical Society 2016, 138
(7)
, 2134-2137. https://doi.org/10.1021/jacs.5b13041
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(1)
, 6-9. https://doi.org/10.1021/acsmedchemlett.5b00488
- Takashi Ooi (Associate Editor) . Virtual Issue Posts on Organocatalysis: Design, Applications, and Diversity. ACS Catalysis 2015, 5
(11)
, 6980-6988. https://doi.org/10.1021/acscatal.5b02354
- Daisuke Urabe, Taro Asaba, and Masayuki Inoue . Convergent Strategies in Total Syntheses of Complex Terpenoids. Chemical Reviews 2015, 115
(17)
, 9207-9231. https://doi.org/10.1021/cr500716f
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(15)
, 4968-4971. https://doi.org/10.1021/jacs.5b02631
- Robert K. Boeckman, Jr., Kyle F. Biegasiewicz, Douglas J. Tusch, and John R. Miller . Organocatalytic Enantioselective α-Hydroxymethylation of Aldehydes: Mechanistic Aspects and Optimization. The Journal of Organic Chemistry 2015, 80
(8)
, 4030-4045. https://doi.org/10.1021/acs.joc.5b00380
- Hirotsugu Suzuki, Io Sato, Yasuhiro Yamashita, and Shu̅ Kobayashi . Catalytic Asymmetric Direct-Type 1,4-Addition Reactions of Simple Amides. Journal of the American Chemical Society 2015, 137
(13)
, 4336-4339. https://doi.org/10.1021/jacs.5b01943
- Zhen Li, Xin Li, Xiang Ni, and Jin-Pei Cheng . Equilibrium Acidities of Proline Derived Organocatalysts in DMSO. Organic Letters 2015, 17
(5)
, 1196-1199. https://doi.org/10.1021/acs.orglett.5b00143
- John M. Brown . Rhodium Asymmetric Hydrogenation Observed during its Exponential Growth Phase. Organometallics 2014, 33
(21)
, 5912-5923. https://doi.org/10.1021/om500780c
- Zhe An, Ying Guo, Liwei Zhao, Zhi Li, and Jing He . l-Proline-Grafted Mesoporous Silica with Alternating Hydrophobic and Hydrophilic Blocks to Promote Direct Asymmetric Aldol and Knoevenagel–Michael Cascade Reactions. ACS Catalysis 2014, 4
(8)
, 2566-2576. https://doi.org/10.1021/cs500385s
- Dai-Huei Jhuo, Bor-Cherng Hong, Chun-Wei Chang, and Gene-Hsiang Lee . One-Pot Organocatalytic Enantioselective Michael–Michael–Aldol–Henry Reaction Cascade. A Facile Entry to the Steroid System with Six Contiguous Stereogenic Centers. Organic Letters 2014, 16
(10)
, 2724-2727. https://doi.org/10.1021/ol501011t
- Chandra M. R. Volla, Iuliana Atodiresei, and Magnus Rueping . Catalytic C–C Bond-Forming Multi-Component Cascade or Domino Reactions: Pushing the Boundaries of Complexity in Asymmetric Organocatalysis. Chemical Reviews 2014, 114
(4)
, 2390-2431. https://doi.org/10.1021/cr400215u
- Na Liu, Anthony Martin, Frédéric Robert, Jean-Marc Vincent, Yannick Landais, Joan Vignolle, Henri Cramail, and Daniel Taton . Polyaldol Synthesis by Direct Organocatalyzed Crossed Polymerization of Bis(ketones) and Bis(aldehydes). Macromolecules 2014, 47
(2)
, 525-533. https://doi.org/10.1021/ma402108y
- Sandra Alcoberro, Alejandro Gómez-Palomino, Ricard Solà, Pedro Romea, Fèlix Urpí, and Mercè Font-Bardia . Stereoselective Titanium-Mediated Aldol Reactions of a Chiral Lactate-Derived Ethyl Ketone with Ketones. Organic Letters 2014, 16
(2)
, 584-587. https://doi.org/10.1021/ol403461b
- Kira Armacost and Orlando Acevedo . Exploring the Aldol Reaction using Catalytic Antibodies and “On Water” Organocatalysts from QM/MM Calculations. Journal of the American Chemical Society 2014, 136
(1)
, 147-156. https://doi.org/10.1021/ja405614p
- Cheng Wang, Dan Wang, and Shuanhu Gao . Total Synthesis of Cyanthiwigins A, C, G, and H. Organic Letters 2013, 15
(17)
, 4402-4405. https://doi.org/10.1021/ol4019425
- Hazit A. Zayas, Annhelen Lu, David Valade, Faheem Amir, Zhongfan Jia, Rachel K. O’Reilly, and Michael J. Monteiro . Thermoresponsive Polymer-Supported l-Proline Micelle Catalysts for the Direct Asymmetric Aldol Reaction in Water. ACS Macro Letters 2013, 2
(4)
, 327-331. https://doi.org/10.1021/mz4000943
- Anil K. Pandey, Devan Naduthambi, Krista M. Thomas, and Neal J. Zondlo . Proline Editing: A General and Practical Approach to the Synthesis of Functionally and Structurally Diverse Peptides. Analysis of Steric versus Stereoelectronic Effects of 4-Substituted Prolines on Conformation within Peptides. Journal of the American Chemical Society 2013, 135
(11)
, 4333-4363. https://doi.org/10.1021/ja3109664
- Keiji Mori, Yuki Ichikawa, Manato Kobayashi, Yukihiro Shibata, Masahiro Yamanaka, and Takahiko Akiyama . Enantioselective Synthesis of Multisubstituted Biaryl Skeleton by Chiral Phosphoric Acid Catalyzed Desymmetrization/Kinetic Resolution Sequence. Journal of the American Chemical Society 2013, 135
(10)
, 3964-3970. https://doi.org/10.1021/ja311902f
- Quan Cai and Shu-Li You . Organocatalyzed Enantioselective Formal [4 + 2] Cycloaddition of 2,3-Disubstituted Indole and Methyl Vinyl Ketone. Organic Letters 2012, 14
(12)
, 3040-3043. https://doi.org/10.1021/ol301114z
- Eusebio Juaristi . Looking for Treasure in Stereochemistry-Land. A Path Marked by Curiosity, Obstinacy, and Serendipity. The Journal of Organic Chemistry 2012, 77
(11)
, 4861-4884. https://doi.org/10.1021/jo300195m
- Vincent Gauchot and Andreea R. Schmitzer . Asymmetric Aldol Reaction Catalyzed by the Anion of an Ionic Liquid. The Journal of Organic Chemistry 2012, 77
(11)
, 4917-4923. https://doi.org/10.1021/jo300737u
- Vikas Sikervar and Philip L. Fuchs . Intramolecular Methylation of an Allyl Sulfone via Lithium Alkoxyaluminate; Application to the Enantioselective Synthesis of the CD Ring of Vitamin D3. Organic Letters 2012, 14
(11)
, 2922-2924. https://doi.org/10.1021/ol301144a
- Qingquan Zhao, Yu-hong Lam, Mahboubeh Kheirabadi, Chongsong Xu, K. N. Houk, and Christian E. Schafmeister . Hydrophobic Substituent Effects on Proline Catalysis of Aldol Reactions in Water. The Journal of Organic Chemistry 2012, 77
(10)
, 4784-4792. https://doi.org/10.1021/jo300569c
- Yu-hong Lam, K. N. Houk, Ulf Scheffler, and Rainer Mahrwald . Stereoselectivities of Histidine-Catalyzed Asymmetric Aldol Additions and Contrasts with Proline Catalysis: A Quantum Mechanical Analysis. Journal of the American Chemical Society 2012, 134
(14)
, 6286-6295. https://doi.org/10.1021/ja2118392
- Pengxin Zhou, Long Zhang, Sanzhong Luo, and Jin-Pei Cheng . Asymmetric Synthesis of Wieland–Miescher and Hajos–Parrish Ketones Catalyzed by an Amino-Acid-Derived Chiral Primary Amine. The Journal of Organic Chemistry 2012, 77
(5)
, 2526-2530. https://doi.org/10.1021/jo202433v
- Blandine Ressault, Alexis Jaunet, Philippe Geoffroy, Sébastien Goudedranche, and Michel Miesch . Access to Polyfunctionalized Diquinanes, Hydrindanes, and Decalines via TiCl4 Promoted Michael–Aldol and Baylis–Hillman Reactions. Organic Letters 2012, 14
(1)
, 366-369. https://doi.org/10.1021/ol203118t
- Bruce H. Lipshutz and Subir Ghorai . Organocatalysis in Water at Room Temperature with In-Flask Catalyst Recycling. Organic Letters 2012, 14
(1)
, 422-425. https://doi.org/10.1021/ol203242r
- Taichi Kano, Hisashi Sugimoto, and Keiji Maruoka . Efficient Organocatalytic Cross-Aldol Reaction between Aliphatic Aldehydes through Their Functional Differentiation. Journal of the American Chemical Society 2011, 133
(45)
, 18130-18133. https://doi.org/10.1021/ja208873k
- Anthony J. Pearson and Santanu Panda . N-Prolinylanthranilamide Pseudopeptides as Bifunctional Organocatalysts for Asymmetric Aldol Reactions. Organic Letters 2011, 13
(20)
, 5548-5551. https://doi.org/10.1021/ol202284n
- Annhelen Lu, Thomas P. Smart, Thomas H. Epps, III, Deborah A. Longbottom, and Rachel K. O’Reilly . l-Proline Functionalized Polymers Prepared by RAFT Polymerization and Their Assemblies as Supported Organocatalysts. Macromolecules 2011, 44
(18)
, 7233-7241. https://doi.org/10.1021/ma201256m
- Louis Marchetti and Mindy Levine . Biomimetic Catalysis. ACS Catalysis 2011, 1
(9)
, 1090-1118. https://doi.org/10.1021/cs200171u
- Lynnie Trzoss, Jing Xu, Michelle H. Lacoske, William C. Mobley, and Emmanuel A. Theodorakis . Enantioselective Synthesis of (−)-Jiadifenin, a Potent Neurotrophic Modulator. Organic Letters 2011, 13
(17)
, 4554-4557. https://doi.org/10.1021/ol201742j
- Karol Michalak and Jerzy Wicha . Total Synthesis of a CD-Ring: Side-Chain Building Block for Preparing 17-epi-Calcitriol Derivatives from the Hajos–Parrish Dione. The Journal of Organic Chemistry 2011, 76
(16)
, 6906-6911. https://doi.org/10.1021/jo201083w
- Masaatsu Adachi, Takema Komada, and Toshio Nishikawa . A New Ring Expansion for a Chiral Hexahydroazulene Skeleton Possessing an Angular Methyl Group. The Journal of Organic Chemistry 2011, 76
(16)
, 6942-6945. https://doi.org/10.1021/jo201153h
- Paul Ha-Yeon Cheong, Claude Y. Legault, Joann M. Um, Nihan Çelebi-Ölçüm, and K. N. Houk . Quantum Mechanical Investigations of Organocatalysis: Mechanisms, Reactivities, and Selectivities. Chemical Reviews 2011, 111
(8)
, 5042-5137. https://doi.org/10.1021/cr100212h
- Albert Moyano and Ramon Rios . Asymmetric Organocatalytic Cyclization and Cycloaddition Reactions. Chemical Reviews 2011, 111
(8)
, 4703-4832. https://doi.org/10.1021/cr100348t
- Markus B. Schmid, Kirsten Zeitler, and Ruth M. Gschwind . Formation and Stability of Prolinol and Prolinol Ether Enamines by NMR: Delicate Selectivity and Reactivity Balances and Parasitic Equilibria. Journal of the American Chemical Society 2011, 133
(18)
, 7065-7074. https://doi.org/10.1021/ja111544b
- Markus B. Schmid, Kirsten Zeitler, and Ruth M. Gschwind . NMR Investigations on the Proline-Catalyzed Aldehyde Self-Condensation: Mannich Mechanism, Dienamine Detection, and Erosion of the Aldol Addition Selectivity. The Journal of Organic Chemistry 2011, 76
(9)
, 3005-3015. https://doi.org/10.1021/jo200431v
- Shuji Yamashita, Kentaro Iso, Kazuki Kitajima, Masafumi Himuro, and Masahiro Hirama . Total Synthesis of Cortistatins A and J. The Journal of Organic Chemistry 2011, 76
(8)
, 2408-2425. https://doi.org/10.1021/jo2002616
- Shu̅ Kobayashi, Yuichiro Mori, John S. Fossey, and Matthew M. Salter . Catalytic Enantioselective Formation of C−C Bonds by Addition to Imines and Hydrazones: A Ten-Year Update. Chemical Reviews 2011, 111
(4)
, 2626-2704. https://doi.org/10.1021/cr100204f
- Zhi-Jun Jia, Hao Jiang, Jun-Long Li, Björn Gschwend, Qing-Zhu Li, Xiang Yin, Julie Grouleff, Ying-Chun Chen, and Karl Anker Jørgensen . Trienamines in Asymmetric Organocatalysis: Diels−Alder and Tandem Reactions. Journal of the American Chemical Society 2011, 133
(13)
, 5053-5061. https://doi.org/10.1021/ja1112194
- José G. Hernández and Eusebio Juaristi . Asymmetric Aldol Reaction Organocatalyzed by (S)-Proline-Containing Dipeptides: Improved Stereoinduction under Solvent-Free Conditions. The Journal of Organic Chemistry 2011, 76
(5)
, 1464-1467. https://doi.org/10.1021/jo1022469
- Jian Xiao, Yun-Peng Lu, Yan-Ling Liu, Poh-Shen Wong, and Teck-Peng Loh . A New Class of Structurally Rigid Tricyclic Chiral Secondary Amine Organocatalyst: Highly Enantioselective Organocatalytic Michael Addition of Aldehydes to Vinyl Sulfones. Organic Letters 2011, 13
(5)
, 876-879. https://doi.org/10.1021/ol102933q
- Pablo Domínguez de María, Paula Bracco, Luiz Fernando Castelhano, and Gerrald Bargeman . Influence of the Organocatalyst in the Aldol/Mannich-Type Product Selectivities in C−C Bond Forming Reactions. ACS Catalysis 2011, 1
(2)
, 70-75. https://doi.org/10.1021/cs100088m
- Hua Yang, Subham Mahapatra, Paul Ha-Yeon Cheong, and Rich G. Carter. Highly Stereoselective and Scalable anti-Aldol Reactions Using N-(p-Dodecylphenylsulfonyl)-2-pyrrolidinecarboxamide: Scope and Origins of Stereoselectivities. The Journal of Organic Chemistry 2010, 75
(21)
, 7279-7290. https://doi.org/10.1021/jo1015008
- Le Li and Daniel Seidel. Catalytic Enantioselective Friedländer Condensations: Facile Access to Quinolines with Remote Stereogenic Centers. Organic Letters 2010, 12
(21)
, 5064-5067. https://doi.org/10.1021/ol1023932
- Guillaume Pousse, Fabien Le Cavelier, Luke Humphreys, Jacques Rouden and Jérôme Blanchet . Brønsted Acid Catalyzed Asymmetric Aldol Reaction: A Complementary Approach to Enamine Catalysis. Organic Letters 2010, 12
(16)
, 3582-3585. https://doi.org/10.1021/ol101176j
- Hua Yang and Rich G. Carter. Synthesis of All-Carbon, Quaternary Center-Containing Cyclohexenones through an Organocatalyzed, Multicomponent Coupling. Organic Letters 2010, 12
(13)
, 3108-3111. https://doi.org/10.1021/ol1011955
- Michael North and Pedro Villuendas. A Chiral Solvent Effect in Asymmetric Organocatalysis. Organic Letters 2010, 12
(10)
, 2378-2381. https://doi.org/10.1021/ol1007313
- F. J. S. Duarte, E. J. Cabrita, G. Frenking and A. Gil Santos . Asymmetric Intramolecular Aldol Reactions of Substituted 1,7-Dicarbonylic Compounds. A Mechanistic Study. The Journal of Organic Chemistry 2010, 75
(8)
, 2546-2555. https://doi.org/10.1021/jo100026h
- Mihály Bartók. Unexpected Inversions in Asymmetric Reactions: Reactions with Chiral Metal Complexes, Chiral Organocatalysts, and Heterogeneous Chiral Catalysts. Chemical Reviews 2010, 110
(3)
, 1663-1705. https://doi.org/10.1021/cr9002352
- Matthew K. Kiesewetter, Eun Ji Shin, James L. Hedrick and Robert M. Waymouth . Organocatalysis: Opportunities and Challenges for Polymer Synthesis. Macromolecules 2010, 43
(5)
, 2093-2107. https://doi.org/10.1021/ma9025948
- Hai-Feng Cui, Ying-Quan Yang, Zhuo Chai, Peng Li, Chang-Wu Zheng, Shi-Zheng Zhu and Gang Zhao. Enantioselective Synthesis of Functionalized Fluorinated Cyclohexenones via Robinson Annulation Catalyzed by Primary−Secondary Diamines. The Journal of Organic Chemistry 2010, 75
(1)
, 117-122. https://doi.org/10.1021/jo902081w
- Matthew K. Kiesewetter, Marc D. Scholten, Nicole Kirn, Ryan L. Weber, James L. Hedrick and Robert M. Waymouth . Cyclic Guanidine Organic Catalysts: What Is Magic About Triazabicyclodecene?. The Journal of Organic Chemistry 2009, 74
(24)
, 9490-9496. https://doi.org/10.1021/jo902369g
- Jessica L. Frie, Christopher S. Jeffrey and Erik J. Sorensen. A Hypervalent Iodine-Induced Double Annulation Enables a Concise Synthesis of the Pentacyclic Core Structure of the Cortistatins. Organic Letters 2009, 11
(23)
, 5394-5397. https://doi.org/10.1021/ol902168g
- Tadashi Ema, Yoshitaka Oue, Kumiko Akihara, Yuki Miyazaki and Takashi Sakai. Stereoselective Synthesis of Bicyclic Tertiary Alcohols with Quaternary Stereocenters via Intramolecular Crossed Benzoin Reactions Catalyzed by N-Heterocyclic Carbenes. Organic Letters 2009, 11
(21)
, 4866-4869. https://doi.org/10.1021/ol9019293
- Sezgin Kiren and Albert Padwa. A Benzannulation Protocol To Prepare Substituted Aryl Amines Using a Michael-Aldol Reaction of β-Keto Sulfones. The Journal of Organic Chemistry 2009, 74
(20)
, 7781-7789. https://doi.org/10.1021/jo9017793
- Steven E. Wheeler, Antonio Moran, Susan N. Pieniazek and K. N. Houk. Accurate Reaction Enthalpies and Sources of Error in DFT Thermochemistry for Aldol, Mannich, and α-Aminoxylation Reactions. The Journal of Physical Chemistry A 2009, 113
(38)
, 10376-10384. https://doi.org/10.1021/jp9058565
- Stefan Bräse, Arantxa Encinas, Julia Keck and Carl F. Nising. Chemistry and Biology of Mycotoxins and Related Fungal Metabolites. Chemical Reviews 2009, 109
(9)
, 3903-3990. https://doi.org/10.1021/cr050001f
- Hua Yang and Rich G. Carter. Asymmetric Construction of Nitrogen-Containing [2.2.2] Bicyclic Scaffolds Using N-(p-Dodecylphenylsulfonyl)-2-pyrrolidinecarboxamide. The Journal of Organic Chemistry 2009, 74
(15)
, 5151-5156. https://doi.org/10.1021/jo9009062
- Alan Armstrong, Yunas Bhonoah and Andrew J. P. White. Constrained β-Proline Analogues in Organocatalytic Aldol Reactions: The Influence of Acid Geometry. The Journal of Organic Chemistry 2009, 74
(14)
, 5041-5048. https://doi.org/10.1021/jo900840v
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