Abstract
The exact location of the sinus node was determined in 25 infant hearts using reconstructive techniques. The sinus node was found to lie on the lateral aspect of the superior cavo-atrial junction in the great majority (22 hearts). In only 3 hearts was it found to straddle the summit of the crest of the right atrial appendage where it is popularly believed to be located. In the majority of instances a single artery supplied the node (in 11 hearts the artery approached posteriorly, and in 10 the artery approached anteriorly), though there was considerable variation in the exact anatomy of the arterial supply. Connections between the sinus node and atrial myocardium were diffuse and abundant but in no instances were tracts of specialised cells observed leaving the node and traversing any distance through the atrial wall. These findings are relevant to the sinus node dysfunction that may follow cardiac surgical procedures.
Full text
PDF




Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Blair D. M., Davies F. Observations on the Conducting System of the Heart. J Anat. 1935 Apr;69(Pt 3):303–325. [PMC free article] [PubMed] [Google Scholar]
- Davies F. THE CONDUCTING SYSTEM OF THE VERTEBRATE HEART. Br Heart J. 1942 Jul;4(3):66–76. doi: 10.1136/hrt.4.3.66. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Evans R., Shaw D. B. Pathological studies in sinoatrial disorder (sick sinus syndrome). Br Heart J. 1977 Jul;39(7):778–786. doi: 10.1136/hrt.39.7.778. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hutchinson M. C. A study of the artrial arteries in man. J Anat. 1978 Jan;125(Pt 1):39–54. [PMC free article] [PubMed] [Google Scholar]
- Isaacson R., Titus J. L., Merideth J., Feldt R. H., McGoon D. C. Apparent interruption of atrial conduction pathways after surgical repair of transposition of great arteries. Am J Cardiol. 1972 Oct;30(5):533–535. doi: 10.1016/0002-9149(72)90044-6. [DOI] [PubMed] [Google Scholar]
- JAMES T. N. Anatomy of the human sinus node. Anat Rec. 1961 Oct;141:109–139. doi: 10.1002/ar.1091410205. [DOI] [PubMed] [Google Scholar]
- JAMES T. N. THE CONNECTING PATHWAYS BETWEEN THE SINUS NODE AND A-V NODE AND BETWEEN THE RIGHT AND THE LEFT ATRIUM IN THE HUMAN HEART. Am Heart J. 1963 Oct;66:498–508. doi: 10.1016/0002-8703(63)90382-x. [DOI] [PubMed] [Google Scholar]
- James T. N. The sinus node. Am J Cardiol. 1977 Dec;40(6):965–986. doi: 10.1016/0002-9149(77)90048-0. [DOI] [PubMed] [Google Scholar]
- Keith A, Flack M. The Form and Nature of the Muscular Connections between the Primary Divisions of the Vertebrate Heart. J Anat Physiol. 1907 Apr;41(Pt 3):172–189. [PMC free article] [PubMed] [Google Scholar]
- LEV M. Aging changes in the human sinoatrial node. J Gerontol. 1954 Jan;9(1):1–9. doi: 10.1093/geronj/9.1.1. [DOI] [PubMed] [Google Scholar]
- Lev M., Bharati S. Lesions of the conduction system and their functional significance. Pathol Annu. 1974;9(0):157–207. [PubMed] [Google Scholar]
- Merideth J., Titus J. L. The anatomic atrial connections btween sinu and A-V node. Circulation. 1968 Apr;37(4):566–579. doi: 10.1161/01.cir.37.4.566. [DOI] [PubMed] [Google Scholar]
- Truex R. C., Smythe M. Q., Taylor M. J. Reconstruction of the human sinoatrial node. Anat Rec. 1967 Dec;159(4):371–378. doi: 10.1002/ar.1091590406. [DOI] [PubMed] [Google Scholar]
- el-Said G., Rosenberg H. S., Mullins C. E., Hallman G. L., Cooley D. A., McNamara D. G. Dysrhythmias after Mustard's operation for transposition of the treat arteries. Am J Cardiol. 1972 Oct;30(5):526–532. doi: 10.1016/0002-9149(72)90043-4. [DOI] [PubMed] [Google Scholar]