α-Difluoromethyl-DOPA

α-Difluoromethyl-DOPA
Names
	Systematic IUPAC name (2S)-2-Amino-2-[(3,4-dihydroxyphenyl)methyl]-3,3-difluoropropanoic acid
	Other names α-(Difluoromethyl)-3-hydroxy-L-tyrosine
Identifiers
CAS Number	160401-53-6 ;
3D model (JSmol)	Interactive image; Interactive image;
ChemSpider	114812 ;
MeSH	alpha-difluoromethyl-DOPA
PubChem CID	129677;
UNII	4FX102BRL6 ;
CompTox Dashboard (EPA)	DTXSID70220233 ;
	InChI InChI=1S/C10H11F2NO4/c11-8(12)10(13,9(16)17)4-5-1-2-6(14)7(15)3-5/h1-3,8,14-15H,4,13H2,(H,16,17)/t10-/m1/s1 Key: XZVHHLNLLVICFA-SNVBAGLBSA-N ; InChI=1/C10H11F2NO4/c11-8(12)10(13,9(16)17)4-5-1-2-6(14)7(15)3-5/h1-3,8,14-15H,4,13H2,(H,16,17)/t10-/m1/s1 Key: XZVHHLNLLVICFA-SNVBAGLBBM;
	SMILES C1=CC(=C(C=C1C[C@@](C(F)F)(C(=O)O)N)O)O; FC(F)[C@](C(=O)O)(N)Cc1cc(O)c(O)cc1;
Properties
Chemical formula	C10H11F2NO4
Molar mass	247.20 g/mol
Density	1.528 g/mL
Boiling point	479 °C (894 °F; 752 K)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

α-Difluoromethyl-3,4-dihydroxyphenylalanine (DFMD, DFM-DOPA) is a DOPA decarboxylase inhibitor.^[1]

References

^ Zbinden G, Brändle E (February 1980). "Inhibition of 5-hydroxytryptophan nephrotoxicity by alpha-difluoromethyl-dopa, an inhibitor or L-amino acid decarboxylase". Toxicology Letters. 5 (2): 125–9. doi:10.1016/0378-4274(80)90161-7. PMID 6781106.