Clofenciclan
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| Trade names | Tonquil, Vesitan |
| Other names | Chlorphencyclan |
| Routes of administration | Oral |
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| Chemical and physical data | |
| Formula | C18H28ClNO |
| Molar mass | 309.88 g·mol−1 |
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Clofenciclan (also known as chlorphencyclan; trade names Tonquil and Vesitan) is a dopamine-releasing agent developed by Boehringer & Soehne in the 1950s.[1][2] It proved unpopular as a treatment because of its pronounced stimulant activity.[3]
Sila analogues of clorphencyclane were developed.[4]
See also
[edit]References
[edit]- ^ Stach K, Winter W (January 1962). "[New therapeutically active basic ethers. 1. 1-Arylcycloalkanol derivatives]". Arzneimittel-Forschung. 12: 25–29. PMID 13916036.
- ^ US 3254083, Stach K, Friesewinkel HA, Kroneberg HG, Stoepel K, Winter W, "[1-(Monocarbocyclic aryl)-cycloalkyl]-[(tertiaryamino)-lower alkyl] ethers", issued 31 May 1966, assigned to Roche Diagnostics GmbH
- ^ Poeldinger W (January 1962). "[Therapeutic experiences with thiopropazate and with a combination of thiopropazate and chlorphencyclan (Vesitan) in psychiatry]". Praxis (in German). 51: 73–78. PMID 14487367.
- ^ Ackermann J, Tacke R, Wannagat U, Koke U, Meyer F (1980). "Sila drugs, XII: Sila analogues of clorphencyclane (Author's transl)". Archiv der Pharmazie. 313 (2): 129–141. doi:10.1002/ardp.19803130206. PMID 7369832.
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